AnaSpec Inc.

In Alzheimer’s disease (AD), the major pathological hallmarks are β-sheet aggregates of β-amyloid peptides in senile plaques and hyperphosphorylated tau protein in neurofibrillary tangles (NFT).1-2

ClearPoint™ peptides offer a choice of heavy carbon (13C), or nitrogen (15N)-isotopes specifically labeled at single or universal positions.

The SensoLyte® 520 TACE Activity Assay Kit uses a FRET peptide substrate for the continuous measurement of enzyme activity.

5-Methylcytidine is a modified base found in the DNA of plants and vertebrate. DNA methylation is a post-replication process involved in the establishment of genomic imprinting, in the control of gene expression and of differentiation.

AnaSpec is pleased to provide Calcein AM at two purity grades, >90% or >95%, as determined by HPLC. AnaSpec also offers the SensoLyte® Calcein Cell Viability Assay Kit - a rapid and sensitive assay to detect viable cells.

Rabbit Anti-human Cathelicidin LL-37 polyclonal antibody was raised against a synthetic peptide from a sequence found within 134-170 amino acid residues (LL-37) of the LL-37 precursor human cationic antimicrobial protein, hCAP-18.

The SensoLyte® 520MMP-15, MMP-16 and MMP-24 Assay Kits provide a convenient assay for high throughput screening (HTS) of inducers and inhibitors for MMP-15, MMP-16 and MMP-24, respectively

The long wavelength of SensoLyte® protease assays, many of which utilize the 5-FAM/QXL™ 520 and HiLyte Fluor™ 488/QXL™ 520 FRET pairs, have revolutionized the industry, setting the gold standard in fluorimetric assay sensitivity.

AnaSpec routinely completes difficult peptide synthesis such as synthesis of long peptides (>90-mers), peptides containing unusual modifications, and cyclic peptides.

Chemists at AnaSpec, Eurogentec Group have developed a Wang resin conjugated with a pNA analog, 5-amino-2-nitrozenzoic acid (Anb5,2).